high plasma homocysteine and insulin resistance in patients with polycystic ovarian syndrome

High plasma homocysteine and insulin resistance in patients with polycystic ovarian syndrome

BACKGROUND Polycystic ovarian syndrome (PCOS) is a common disease among women in fertility ages and cause severe insulin resistance. Hyperhomocysteinaemia is said to be among the features of PCOS that could influence its outcome. OBJECTIVE This study aimed to investigate whether hyperhomocysteinaemia exists in PCOS and if it is related to insulin resistance in the affected patients. MATERIA...

Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome

Insulin Resistance in First-Degree Relatives of the Patients with Polycystic Ovarian Syndrome

Abstract Objective: Insulin resistance and hyperinsulinemia are common among the women with polycystic ovarian syndrome (PCOS). Familial aggregation of PCOS has implications on the role of heredity in this disease. The aim of this study was to evaluate insulin resistance among the fathers, mothers, and siblings of the women with PCOS referring to the clinics affiliated to Shiraz University of ...

The Plasma Homocysteine Concentrations and Relationship with Insulin Resistance in Young Women with Polycystic Ovary Syndrome

Women with polycystic ovary syndrome (PCOS) have several cardiovascular disease risk factors including hyperinsulinemia. Hyperhomocysteinemia is a recognized risk factor for atherosclerosis and has recently to be correlated positively with the hyperinsulinemia. We examined the relationship between plasma homocysteine levels and insulin resistance in patients with PCOS. Forty women with PCOS and...

Insulin resistance and polycystic ovarian syndrome.

Insulin resistance (IR) and polycystic ovarian syndrome (PCOS) appear as linked phenomena, although this is not easy to obviate in common forms of PCOS while it is evident in the rare cases of extreme IR and hyperinsulinism (HI). Experimental data indicate that insulin could interfere with the local insulin-like growth factor systems in ovaries, and presumably in adrenals and in the hypothalami...

Assessment of Homocysteine Level in Plasma of Iraqi Women with Polycystic Ovary Syndrome and Insulin Resistance

Polycystic ovary syndrome (PCOS) is a common endocrine disorder which affects women at reproductive age. This study was aimed to detect homocysteine level in women with polycystic ovary syndrome. The present study was carried out for (51) PCOS women and (10) healthy women as controls at High Institute for Infertility Diagnosis and Assisted Reproductive Technologies/AL-Nahrain University, from F...